12. Amyloidosis renis (HE).

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12. Amyloidosis renis (HE).
Amyloid appears as a homogeneous, pink colored by eozina, structureless substance in renal structures. Glomeruli are affected to varying degrees - from the homogenization of individual capillaries in the early stage, to cover all the glomeruli of the process. Damaged glomeruli are larger than normal as a result of their accumulation of abnormal protein. Shows the preparation and accumulation of pink colored protein in the walls of vessels of medium and small caliber and in the basal membrane of the seminiferous that are thickened. The process leads to fatty degeneration in epithelial cells them due to chronic hypoxia associated with reduction in glomerular blood flow. Fatty degeneration of the epithelial cells of proximal tubules is the cause of macroscopic findings "ren albus".

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